50-168-4878

XPF Mouse anti-Canine, Human, Mouse, Rat, Clone: UMAB21, lyophilized, UltraMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-4878-Each-of-1 In Stock ₹ 65,489.76

50-168-4878 - Each of 1

₹ 65,489.76

In Stock

Quantity

1

Base Price: ₹ 65,489.76

GST (18%): ₹ 11,788.157

Total Price: ₹ 77,277.917

Antigen

XPF

Classification

Monoclonal

Conjugate

Unconjugated

Gene

ERCC4

Gene Alias

ERCC11, FANCQ, RAD1, XFEPS, XPF

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2072, 304719, 479842, 50505

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array

Clone

UMAB21

Formulation

PBS with 8% trehalose and no preservative

Gene Accession No.

Q92889, Q9QZD4

Gene Symbols

Ercc4

Immunogen

Full length human recombit protein of human XPF produced in HEK293 cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Related Products

Img

OriGene

50-168-4876

--

Img

OriGene

50-168-4880

--

Img

OriGene

50-166-2045

--

Img

OriGene

50-168-4877

--

Img

OriGene

50-166-2031

--

Img

OriGene

50-168-4875

--

Img

OriGene

50-168-5062

--

Img

OriGene

50-168-5061

--

Description

  • The structure specific ERCC 1 / XPF endonuclease complex is implicated in the repair of two distinct types of lesions in DNA: NER for UV induced lesions and bulky chemical adducts; and recombination repair of the very genotoxic interstrand cross links
  • NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases
  • In mammalian cells, XPG cleaves 3′ of the DNA lesion while the ERCC1 / XPF complex makes the 5′ incision
  • ERCC1 / XPF probably plays a role in processing partially processed recombination intermediates.