50-168-5062

XPF Mouse anti-Canine, Human, Mouse, Rat, Clone: UMAB21, liquid, UltraMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-5062-Each-of-1 In Stock ₹ 22,926.40

50-168-5062 - Each of 1

₹ 22,926.40

In Stock

Quantity

1

Base Price: ₹ 22,926.40

GST (18%): ₹ 4,126.752

Total Price: ₹ 27,053.152

Antigen

XPF

Classification

Monoclonal

Concentration

0.5-1.0 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q92889, Q9QZD4

Gene Symbols

Ercc4

Immunogen

Full length human recombit protein of human XPF produced in HEK293 cell.

Quantity

30 μL

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone

UMAB21

Conjugate

Unconjugated

Gene

ERCC4

Gene Alias

ERCC11, FANCQ, RAD1, XFEPS, XPF

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2072, 304719, 479842, 50505

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • The structure specific ERCC 1 / XPF endonuclease complex is implicated in the repair of two distinct types of lesions in DNA: NER for UV induced lesions and bulky chemical adducts; and recombination repair of the very genotoxic interstrand cross links
  • NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases
  • In mammalian cells, XPG cleaves 3′ of the DNA lesion while the ERCC1 / XPF complex makes the 5′ incision
  • ERCC1 / XPF probably plays a role in processing partially processed recombination intermediates.