50-169-28

IL-6 Monoclonal Antibody (MQ2-13A5), Alexa Fluor™ 700, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-169-28-Each-of-1 In Stock ₹ 33,197.00

50-169-28 - Each of 1

₹ 33,197.00

In Stock

Quantity

1

Base Price: ₹ 33,197.00

GST (18%): ₹ 5,975.46

Total Price: ₹ 39,172.46

Antigen

IL-6

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P05231

Gene Symbols

Il6

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3569

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

MQ2-13A5

Conjugate

Alexa Fluor 700

Gene

Il6

Gene Alias

B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6

Host Species

Rat

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The MQ2-13A5 antibody reacts with human interleukin-6 (IL-6), a 21-28 kDa cytokine secreted by a variety of cell types
  • Applications Reported: This MQ2-13A5 antibody has been reported for use in intracellular staining followed by flow cytometric analysis
  • Applications Tested: This MQ2-13A5 antibody has been pre-titrated and tested by intracellular staining and flow cytometric analysis of stimulated normal human peripheral blood cells using the Intracellular Fixation & Permeabilization Buffer Set (cat
  • 88-8824) and protocol
  • Please refer to Best Protocols: Protocol A: Two step protocol for (cytoplasmic) intracellular proteins located under the Resources Tab online
  • This can be used at 5 μL (0.06 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Alexa Fluor™ 700 emits at 723 nm and can be excited with the red laser (633 nm)
  • Most instruments will require a 685 LP mirror and 710/20 filter
  • Please make sure that your instrument is capable of detecting this fluorochrome
  • Excitation: 633-647 nm; Emission: 723 nm; Laser: Red Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • IL-6 is a gene that encodes a cytokine that plays a role in inflammation and the maturation of B cells
  • The protein produced by this gene is an endogenous pyrogen that can induce fever in people with autoimmune diseases or infections
  • The gene is primarily expressed at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha
  • The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis
  • Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2)
  • Diseases associated with IL6 include Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile.