50-177-76

IL-2 Monoclonal Antibody (B-G5), eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-177-76-Each-of-1 In Stock ₹ 21,627.00

50-177-76 - Each of 1

₹ 21,627.00

In Stock

Quantity

1

Base Price: ₹ 21,627.00

GST (18%): ₹ 3,892.86

Total Price: ₹ 25,519.86

Antigen

IL-2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P60568

Gene Symbols

IL2

Immunogen

Rec. Human IL-2

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Functional Assay

Clone

B-G5

Conjugate

Unconjugated

Gene

IL2

Gene Alias

aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3558

Content And Storage

4° C

Form

Liquid

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Description

  • Description: BMS128 (B-G5) detects IL-2 which has a predicted molecular weight of approximately 15 kDa
  • BMS128 targets IL-2 in ELISA, and WB applications and shows reactivity with Human samples
  • 50 ng of B-G5 neutralizes 1 unit of IL-2 on CTL.L2, inhibition of proliferation by 50%
  • Applications Tested: Functional Studies
  • Purity: >95%
  • Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages
  • IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7)
  • The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene
  • The targeted disruption of a gene similar to IL-2 in mice leads to an μgcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.