50-172-6069
TUSC4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-172-6069-Each-of-1 | In Stock | ₹ 44,150.23 |
50-172-6069 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,150.23
GST (18%): ₹ 7,947.041
Total Price: ₹ 52,097.271
Antigen
TUSC4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NPRL2
Gene Alias
G21 protein, Gene 21 protein, tumor suppressor candidate 4, TUSC4
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10641, 363138, 56032
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
0.26 mg/mL
Formulation
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.
Q8WTW4, Q9WUE4
Gene Symbols
Nprl2
Immunogen
TUSC4 Fusion Protein Ag0210
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- NPRL2, also known as TUSC4 (tumor suppressor candidate 4), is a 380 amino acid protein that contains a bipartite nuclear localization signal and a granulin protein-binding domain
- It is highly expressed in skeletal muscle, followed by brain, liver and pancreas, with lower expression in lung, kidney, placenta and heart
- NPRL2 is also expressed in most lung cancer cell lines and may be involved in tumor suppression
- NPRL2 may play a role in mismatch repair, cell cycle checkpoint signaling and activation of apoptotic pathways
- It may also enhance the therapeutic efficacy of chemotherapy drugs such as cis-platin by resensitizing patients resistant to cisplatin treatment
- The gene encoding NPRL2 is conserved between species and is expressed as two isoforms due to alternative splicing events.