50-172-6155
HDAC3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-172-6155-Each-of-1 | In Stock | ₹ 44,150.23 |
50-172-6155 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,150.23
GST (18%): ₹ 7,947.041
Total Price: ₹ 52,097.271
Antigen
HDAC3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
HDAC3
Gene Alias
HD3, HDAC3, histone deacetylase 3, RPD3, RPD3 2, SMAP45
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
15183, 84578, 8841
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
0.27 mg/mL
Formulation
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.
O15379, O88895, Q6P6W3
Gene Symbols
Hdac3
Immunogen
HDAC3 Fusion Protein Ag0396
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is a rabbit polyclonal antibody raised against an internal region of human HDAC3
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates
- Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events
- Histone deacetylases act via the formation of large multiprotein complexes
- Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 ′Lys-27′ (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activity and repressing proximal gene expression
- Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity
- Required to repress transcription of the POU1F1 transcription factor
- Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation
- Contributes, together with XBP1 isoform 1, to the activation of NFE2L2-mediated HMOX1 transcription factor gene expression in a PI(3)K/mTORC2/Akt-dependent signaling pathway leading to endothelial cell (EC) survival under disturbed flow/oxidative stress (By similarity).