50-172-6267
ID3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-172-6267-Each-of-1 | In Stock | ₹ 44,150.23 |
50-172-6267 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,150.23
GST (18%): ₹ 7,947.041
Total Price: ₹ 52,097.271
Antigen
ID3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ID3
Gene Alias
1R21, bHLHb25, HEIR 1, HEIR1, ID3, Inhibitor of DNA binding 3
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
15903, 25585, 3399
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
0.4 mg/mL
Formulation
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.
P41133, P41138, Q02535
Gene Symbols
ID3
Immunogen
ID3 Fusion Protein Ag0588
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Members of the Id family of basic helix-loop-helix (bHLH) proteins include ID1, ID2, ID3 and ID4
- They are ubiquitously expressed and dimerize with members of the class A and B HLH proteins
- Due to the absence of the basic region, the resulting heterodimers cannot bind DNA
- The ID-type proteins thus appear to negatively regulate DNA binding of bHLH proteins
- Since ID1 inhibits DNA binding of E12 and Myo D, it apparently functions to inhibit muscle-specific gene expression
- Under conditions that facilitate muscle cell differentiation, the ID protein levels fall, allowing E12 and/or E47 to form heterodimers with Myo D and myogenin, which in turn activate myogenic differentiation
- It has been shown that expression of each of the ID proteins is strongly dependent on growth factor activation and that reduction of ID mRNA levels by antisense oligonucleotides leads to a delayed reentry of arrested cells into the cell cycle following growth factor stimulation.