50-172-6509
TPMT Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-172-6509-Each-of-1 | In Stock | ₹ 44,150.23 |
50-172-6509 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,150.23
GST (18%): ₹ 7,947.041
Total Price: ₹ 52,097.271
Antigen
TPMT
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TPMT
Gene Alias
Thiopurine methyltransferase, thiopurine S methyltransferase, TPMT
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22017, 690050, 7172
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.15 mg/mL
Formulation
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.
O55060, P51580, Q9Z0T0
Gene Symbols
TPMT
Immunogen
TPMT Fusion Protein Ag1074
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody specifically recognizes the 34 kDa protein
- Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine
- Defects in TPMT are the cause of thiopurine S-methyltransferase deficiency (TPMT deficiency)
- TPMT is an enzyme involved in the normal metabolic inactivation of thiopurine drugs
- These drugs are generally used as immunosupressants or cytotoxic drugs and are prescribed for a variety of clinical conditions including leukemia, autoimmune disease and organ transplantation
- Patients with intermediate or no TPMT activity are at risk of toxicity after receiving standard doses of thiopurine drugs and it is shown that inter-individual differences in response to these drugs are largely determined by genetic variation at the TPMT locus.