50-172-7706

G0S2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-172-7706-Each-of-1 In Stock ₹ 44,150.23

50-172-7706 - Each of 1

₹ 44,150.23

In Stock

Quantity

1

Base Price: ₹ 44,150.23

GST (18%): ₹ 7,947.041

Total Price: ₹ 52,097.271

Antigen

G0S2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

G0S2

Gene Alias

G0/G1switch 2, G0S2, RP1 28O10.2

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14373, 50486

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Western Blot

Concentration

0.17 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

P27469, Q61585

Gene Symbols

G0S2

Immunogen

G0S2 Fusion Protein Ag2731

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Description The G(0)-G(1) switch gene 2 (G0S2) codes for a mitochondrial protein that is important in apoptosis, lipolysis, and triacylglycerol hydrolysis
  • In adipocytes, G0S2 binds to adipose triglyceride lipase and decreases the breakdown of lipid droplets
  • In Crohn′s colitis, the presence of G0S2 is increased in correlation to the amount of non-converted lipid in waste
  • In squamous lung cancer, mutations in the G0S2 gene are common
  • In breast cancer, epigenetic silencing of G0S2 occurs, and normal apoptotic regulation of aberrant cells is negatively impacted
  • However, when G0S2 is not epigenetically modified, it is the best mediator of the Bcl-2/Bax heterodimer, resulting in apoptosis of cancerous cells.