50-172-9698

COMT Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-172-9698-Each-of-1 In Stock ₹ 44,150.23

50-172-9698 - Each of 1

₹ 44,150.23

In Stock

Quantity

1

Base Price: ₹ 44,150.23

GST (18%): ₹ 7,947.041

Total Price: ₹ 52,097.271

Antigen

COMT

Classification

Polyclonal

Conjugate

Unconjugated

Gene

COMT

Gene Alias

catechol O methyltransferase, COMT

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12846, 1312, 24267

Content And Storage

-20°C

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation

Concentration

0.19 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O88587, P21964, P22734

Gene Symbols

COMT

Immunogen

COMT Fusion Protein Ag6502

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • COMT (Catechol-O-methyltransferase) catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine
  • This O-methylation results in one of the major degradative pathways of the catecholamine transmitters
  • In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease
  • COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT)
  • The differences between S-COMT and MB-COMT reside within the N-termini
  • Several transcript variants are formed through the use of alternative translation initiation sites and promoters.