50-173-0000

GSTO1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-0000-Each-of-1 In Stock ₹ 44,150.23

50-173-0000 - Each of 1

₹ 44,150.23

In Stock

Quantity

1

Base Price: ₹ 44,150.23

GST (18%): ₹ 7,947.041

Total Price: ₹ 52,097.271

Antigen

GSTO1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GSTO1

Gene Alias

GSTO 1, GSTO1, GSTTLp28, P28

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

114846, 14873, 9446

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

0.3 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O09131, P78417, Q9Z339

Gene Symbols

GSTO1

Immunogen

GSTO1 Fusion Protein Ag7199

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody detects both monomer (27-30 kDa) and dimer forms of GSTO1 (54-64 kDa)
  • GSTO1 (glutathione S-transferase omega 1), also known as p28 or GSTTLp28, is a 241 amino acid protein that localizes to the cytoplasm and contains both an N-terminal and a C-terminal GST domain
  • Expressed ubiquitously with highest expression in heart, liver and skeletal muscle, GSTO1 exists as a homodimer that functions as both a glutathione-dependent thiol transferase and a dehydroascorbate reductase
  • Specifically, GSTO1 catalyzes the reaction of glutathione with a wide variety of organic compounds to form thioethers, a process that is essential for the metabolism and detoxification of a variety of xenobiotics and carcinogens
  • Human GSTO1 shares 70% sequence homology with its rodent counterpart, suggesting a conserved role between species
  • Polymorphisms in the gene encoding GSTO1 may be associated with the development of childhood acute lymphoblastic leukemia, Parkinson′s disease and Alzheimer disease.