50-173-1032

POLR3B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-1032-Each-of-1 In Stock ₹ 44,150.23

50-173-1032 - Each of 1

₹ 44,150.23

In Stock

Quantity

1

Base Price: ₹ 44,150.23

GST (18%): ₹ 7,947.041

Total Price: ₹ 52,097.271

Antigen

POLR3B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

POLR3B

Gene Alias

C128, POLR3B, RNA polymerase III subunit C2, RPC2

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

362858, 55703, 70428

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

0.13 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P59470, Q9NW08

Gene Symbols

Polr3b

Immunogen

POLR3B Fusion Protein Ag9856

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Members of the Protein kinase C (PKC) family of serine/threonine protein kinases are grouped by their activation mechanism
  • Classical or conventional PKCs (PKC alpha-, betaI- , betaII- and gamma-) are activated by phosphatidylserine in a calcium dependent manner and can bind diacylglycerol
  • The Ca2+ insensitive novel PKCs (PKCs epsilon-, delta-, theta- and eta) are also activated by diacylglycerol and phosphatidylserine
  • The atypical PKCs (PKCs iota- and zeta-) are insensitive to Ca2+, DAG and phorbolesters
  • All PKCs isoforms consist of a highly conserved catalytic domain connected to a regulatory domain via a hinge region
  • PKCs are involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, tumorigenesis, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascades involving MAPK1/3 (ERK1/2) and RAP1GAP.