50-173-0671

POLR3F Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-0671-Each-of-1 In Stock ₹ 44,150.23

50-173-0671 - Each of 1

₹ 44,150.23

In Stock

Quantity

1

Base Price: ₹ 44,150.23

GST (18%): ₹ 7,947.041

Total Price: ₹ 52,097.271

Antigen

POLR3F

Classification

Polyclonal

Conjugate

Unconjugated

Gene

POLR3F

Gene Alias

POLR3F, RNA polymerase III subunit C6, RPC39, RPC6

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10621, 311487, 70408

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Western Blot

Concentration

0.18 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q921X6, Q9H1D9

Gene Symbols

Polr3f

Immunogen

POLR3F Fusion Protein Ag8935

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The human POLR3F is a component of RNA III polymerase
  • RNA polymerase III transcribes many essential, small, noncoding RNAs, including the 5S rRNAs and tRNAs
  • While most pol III-transcribed genes are found scattered throughout the linear chromosome maps or in multiple linear clusters, there is increasing evidence that many of these genes prefer to be spatially clustered, often at or near the nucleolus
  • This association could create an environment that fosters the coregulation of transcription by pol III with transcription of the large ribosomal RNA repeats by RNA polymerase I (pol I) within the nucleolus
  • Given the high number of pol III-transcribed genes in all eukaryotic genomes, the spatial organization of these genes is likely to affect a large portion of the other genes in a genome
  • POLR3F has also been recently identified as an HIV dependency factor (HDF), suggesting that POLR3F may be an important drug target in HIV treatment
  • At least two isoforms of POLR3F are known to exist.