50-173-3746
TRIM72 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-173-3746-Each-of-1 | In Stock | ₹ 44,150.23 |
50-173-3746 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,150.23
GST (18%): ₹ 7,947.041
Total Price: ₹ 52,097.271
Antigen
TRIM72
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TRIM72
Gene Alias
hMG53, Mg53, Mitsugumin 53, TRIM72, tripartite motif containing 72
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
434246, 493829
Content And Storage
-20°C
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
0.77 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q1XH17, Q6ZMU5
Gene Symbols
Trim72
Immunogen
TRIM72 Fusion Protein Ag17756
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites
- Specifically binds phosphatidylserine
- Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site
- This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation
- Probably acts upstream of the Ca(2+)-dependent membrane resealing process
- Required for transport of DYSF to sites of cell injury during repair patch formation
- Regulates membrane budding and exocytosis
- May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles.