50-173-3783
FOXP3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-173-3783-Each-of-1 | In Stock | ₹ 44,150.23 |
50-173-3783 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,150.23
GST (18%): ₹ 7,947.041
Total Price: ₹ 52,097.271
Antigen
FOXP3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
FOXP3
Gene Alias
AIID, DIETER, forkhead box P3, Forkhead box protein P3, FOXP3, IPEX, JM2, PIDX, Scurfin, XPID
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20371, 317382, 50943
Content And Storage
-20°C
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
0.29 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q99JB6, Q9BZS1
Gene Symbols
Foxp3
Immunogen
FOXP3 Fusion Protein Ag17571
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is a rabbit polyclonal antibody raised against a peptide mapping within human FOXP3
- FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis
- FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells
- FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells
- Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice
- In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome
- Transcript variants of FOXP3 encoding different isoforms have been identified
- In human breast and colon cancer cells, expression of FOXP3 is regulated by p53 in response to the DNA damage.