50-198-2145

THEMIS Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

Select a Size

Pack Size SKU Availability Price
Each of 1 50-198-2145-Each-of-1 In Stock ₹ 38,381.25

50-198-2145 - Each of 1

₹ 38,381.25

In Stock

Quantity

1

Base Price: ₹ 38,381.25

GST (18%): ₹ 6,908.625

Total Price: ₹ 45,289.875

Antigen

THEMIS

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Themis

Gene Alias

bA325O24.3; bA325O24.4; C6orf190; C6orf207; E430004N04Rik; FLJ40584; Gasp; GRB2-associated protein; Grb2-associating protein; MGC163388; Protein THEMIS; Protein thylex; RGD1560849; signaling phosphoprotein specific for T cells; Spot; Themis; thylex; thymocyte expressed molecule involved in selection; thymocyte selection associated; thymocyte selection pathway associated; Thymocyte-expressed molecule involved in selection; TSEPA

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

387357

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q8N1K5

Gene Symbols

Themis

Immunogen

KLH conjugated synthetic peptide derived from human THEMIS.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Themis is a cytoplasmic protein that is essential for positive selection and the development of single-positive thymocytes
  • Highest levels of expression are found in CD4+CD8+ double-positive thymocytes, with lower expression found in mature T cells
  • In addition to Grb1, Themis has been found to associate with PLC gamma 1 and LAT and is quickly phosphorylated by SLP-76 following TCR signaling
  • There are 5 isoforms of mouse Themis that are produced as a result of alternative splicing.