Phospho-alpha B Crystallin (Ser59) Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-2259-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-2259 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
Phospho-alpha B Crystallin (Ser59)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Cryab
Gene Alias
AACRYA; alpha B-crystallin; Alpha(B)-crystallin; alpha-B-crystallin; Alpha-crystallin B chain; alpha-crystallin B chain-like protein; BOS_14343; CMD1II; CRYA2; Crya-2; Cryab; CryAB antibody; crystallin alpha B; crystallin, alpha 2; crystallin, alpha B; crystallin, alpha polypeptide 2; CTPP2; CTRCT16; epididymis secretory protein Li 101; Heat shock protein beta-5; heat shock protein CryAB; heat shock protein HspB5; heat-shock 20 kD like-protein; HEL-S-101; HSPB5; MFM2; P23; Renal carcinoma antigen NY-REN-27; Rosenthal fiber component
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
1410
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
P02511
Gene Symbols
Cryab
Immunogen
KLH conjugated synthetic phosphopeptide derived from human alpha B Crystallin around the phosphorylation site of Ser59.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Lens proteins consist almost entirely of crystallins (about 95%)
- Crystallins are also found vertebrate skeletal muscle tissue
- In the lens, their structural function is to assist in maintaining the proper refractive index of the lens
- The mammalian lens contains 3 major classes of crystallins: alpha, beta, and gamma
- Alpha-crystallin is the largest of the crystallins and is composed of 2 primary gene products-alpha-A and alpha-B
- There are at least 5 different proteins comprising the beta-crystallins
- The gamma-crystallins are monomeric, but there are at least 5 gamma crystallins identified in bovine and rat lens
- Alpha-Crystallin comprises 40% of total lens protein composition
- In addition to maintaining proper refractive index, it also functions in a chaperone like manner by preventing the formation of aggregates possibly leading to cataract formation
- It is believed that the phosphorylated states of the alpha-crystallin occur in response to cellular stress and may serve a structural control function and play a role in protein maintenance
- Alpha-B crystallin has been linked to Alexander′s disease where it accumulates in brain cells of those afflicted.