Phospho-Girdin (Tyr1765) Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-2835-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-2835 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
Phospho-Girdin (Tyr1765)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CCDC88A
Gene Alias
A430106J12Rik; AI848406; Akt phosphorylation enhancer; Akt-phosphorylation enhancer; APE; C130096N06Rik; C330012F17Rik; CCDC88A; coiled coil domain containing 88A; coiled-coil domain containing 88A; Coiled-coil domain-containing protein 88A; D130005J21Rik; G alpha-interacting vesicle-associated protein; Galpha-interacting vesicle-associated protein; Girders of actin filament; girders of actin filaments; Girdin; GIV; GRDN; HkRP1; Hook-related protein 1; Kiaa1212; RGD1306694
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
55704
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q3V6T2
Gene Symbols
CCDC88A
Immunogen
KLH conjugated synthetic phosphopeptide derived from human APE around the phosphorylation site of Ser1765.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Girdin is a Galpha-interacting protein that can enhance the activation of the protein kinase Akt, remodel the actin cytoskeleton, and is thought to be involved in the regulation of cell migration and cancer metastasis
- It has recently been shown that Girdin interacts with Disrupted-in-Schizophrenia 1 (DISC1), a susceptibility gene for major psychiatric disorders
- DISC1 is thought to be involved in the migration, positioning and differentiation of dentate granule cells (DGCs) during development; depletion of Girdin or blocking the Girdin-DISC1 interaction results in defects in axonal sprouting in the CA3 region of the hippocampus and overextended migration of mispositioning of DGCs, suggesting the Girdin plays a role in postnatal neurogenesis in the dentate gyrus.