50-198-4763

CD5L/Api6 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

Select a Size

Pack Size SKU Availability Price
Each of 1 50-198-4763-Each-of-1 In Stock ₹ 38,381.25

50-198-4763 - Each of 1

₹ 38,381.25

In Stock

Quantity

1

Base Price: ₹ 38,381.25

GST (18%): ₹ 6,908.625

Total Price: ₹ 45,289.875

Antigen

CD5L/Api6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cd5l

Gene Alias

1/6; AAC-11; AI047839; Aim; AIM/Spalpha; API6; apoptosis inhibitor 6; Apoptosis inhibitor expressed by macrophages; apoptosis inhibitor of macrophage; Apoptosis inhibitory 6; CD5 antigen-like; CD5 antigen-like (scavenger receptor cysteine rich family); CD5 molecule like; CD5 molecule-like; CD5L; CT2; CT-2; hAIM; IgM-associated peptide; mAIM; Pdp; Pdp 1/6; PRO229; Spalpha; SP-alpha; UNQ203/PRO229

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

922

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O43866

Gene Symbols

Cd5l

Immunogen

KLH conjugated synthetic peptide derived from human CD5L.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5
  • It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection
  • AIM was also shown to support macrophage survival and enhance their phagocytic function
  • More recent experiments using recombinant AIM significantly inhibited apoptosis of NKT and T cells obtained from C
  • parvum -stimulated livers in vitro , suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection.