Phospho-Estrogen Receptor alpha (Ser104, Ser106) Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-5164-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-5164 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
Phospho-Estrogen Receptor alpha (Ser104, Ser106)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ESR1
Gene Alias
BOS_9943; DKFZp686N23123; ER; Er alpha; ER36; Era; ERalpha; ER-alpha; ESR; Esr1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor alpha-like; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; LOC100351261; NR3A1; nuclear receptor; Nuclear re
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
13982, 2099, 24890
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
P03372, P06211, P19785
Gene Symbols
ESR1
Immunogen
KLH conjugated synthetic phosphopeptide derived from human ER alpha around the phosphorylation site of Ser104/106.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors
- The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA
- When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins
- There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively)
- Due to alternative RNA splicing, at least 4 estrogen receptor-alpha isoforms are known to exist (Isoform 1 (66 kDa), Isoform 2 (53 kDa), Isoform 3 (47 kDa), Isoform 4 (35 kDa))
- Estrogen receptors are widely expressed in different tissue types and are essential for sexual development and reproductive function
- They also play a role in other tissues such as bone
- Estrogen receptors are involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.