Phospho-Nur77 (Ser351) Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-5301-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-5301 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
Phospho-Nur77 (Ser351)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NR4A1
Gene Alias
Early response protein NAK1; Gfrp; GFRP1; growth factor-inducible nuclear protein N10; Hbr1; Hbr-1; HMR; hormone receptor; immediate early gene transcription factor NGFI-B; MGC9485; N10; NAK1; NAK-1; nerve growth factor IB nuclear receptor variant 1; nerve growth factor induced protein I-B; Nerve growth factor-induced protein I-B; Ngfib; NGFI-B; NP10; NR4A1; Nuclear hormone receptor NUR/77; Nuclear protein N10; Nuclear receptor subfamily 4 group A member 1; nuclear receptor subfamily 4, group A, member 1; Nur77; Orphan nuclear receptor HMR; Orphan nuclear receptor TR3; Orphan receptor tr3; ST-59; steroid receptor TR3; Testicular receptor 3; TIS1; TR3; TR3 orphan receptor
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3164
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
P22736
Gene Symbols
NR4A1
Immunogen
KLH conjugated synthetic phosphopeptide derived from human Nur77 around the phosphorylation site of Ser351.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily
- NGFI-B-alpha is expressed in brain, adrenal, thyroid, liver, testis, ovary, thymus, muscle, lung and prostate
- Its expression is induced in response to various stress stimuli and growth factors
- The encoded protein acts as a nuclear transcription factor involved in mediating apoptotic signaling in thymocytes and tumor cells, as well as having a role in signaling in the hypothalamic-pituitary axis
- Translocation of the protein from the nucleus to mitochondria induces apoptosis
- Three transcript variants encoding two distinct isoforms have been identified for this NR4A1
- Variant (3), also known as TRC beta, contains multiple differences compared to variant 1
- The resulting isoform b contains a shorter and distinct C-terminus compared to isoform a
- RXR has been shown to be a partner for NR4A1.