Phospho-Rb/P105 RB (Ser807, Ser811) Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-5355-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-5355 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
Phospho-Rb/P105 RB (Ser807, Ser811)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RB1
Gene Alias
Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; Rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; Retinoblastoma 1 (including osteosarcoma); retinoblastoma protein; retinoblastoma suspectibility protein; Retinoblastoma-associated protein
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
19645, 24708, 5925
Content And Storage
-20°C
Form
Liquid
Applications
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
P06400, P13405, P33568
Gene Symbols
RB1
Immunogen
KLH conjugated synthetic phosphopeptide derived from human P105 RB around the phosphorylation site of Ser807/Ser811.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA
- It is phosphorylated on serine and threonine, but not on tyrosine residues
- It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E
- Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth
- Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.