Phospho-Syk (Tyr525, Tyr526) Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss
Manufacturer: Bioss
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-5396-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-5396 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
Phospho-Syk (Tyr525, Tyr526)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Syk
Gene Alias
DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; Spleen tyrosine kinase; Syk; Sykb; Tyrosine-protein kinase SYK
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
20963, 25155, 6850
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
P43405, P48025, Q64725
Gene Symbols
Syk
Immunogen
KLH conjugated synthetic phosphopeptide derived from human Syk around the phosphorylation site of Tyr525/526.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Syk is a cytoplasmic protein tyrosine kinase that translocates to the plasma membrane upon B cell antigen receptor (BCR) or the high-affinity IgE receptor (FcepsilonRI) triggering, and phosphorylates downstream adaptor proteins, thereby providing docking sites for initiation of subsequent signaling pathways, such as calcium mobilization, cytoskeleton remodeling, or transcription of specific genes
- Syk binds to the receptor assemblies through interactions of its pair of SH2 domains with ITAM motives of the receptor, which have been phosphorylated by Src-family kinases
- These kinases also help to activate Syk by phosphorylation of its activation loop.