50-199-1565
POLKGoat anti-Human, Polyclonal, Rockland™
Manufacturer: Rockland Immunochemicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-1565-Each-of-1 | In Stock | ₹ 52,930.08 |
50-199-1565 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,930.08
GST (18%): ₹ 9,527.414
Total Price: ₹ 62,457.494
Antigen
POLK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
POLK
Gene Alias
BOS_10072; DinB homolog 1; DINB protein; DINB1; DINP; DNA damage-inducible protein b; DNA polymerase kappa; DNA-directed DNA polymerase kappa; Polk; POLQ; polymerase (DNA directed) kappa; polymerase (DNA directed), kappa; polymerase (DNA) kappa
Host Species
Goat
Regulatory Status
RUO
Gene ID (Entrez)
51426
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Immunoprecipitation, Western Blot
Concentration
1.4 mg/mL
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.
Q9UBT6
Gene Symbols
POLK
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This affinity purified antibody is directed against human POLK protein
- A BLAST analysis was used to suggest reactivity with this protein from human, chimpanzee and orangutan based on 100% homology for the immunogen sequence
- Cross reactivity with POLK protein from mouse is expected, as this sequence is highly homologous in human and mouse
- Expect reactivity with multiple splice variants of this protein
- Cross reactivity with POLK homologues from other sources has not been determined
- External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells
- Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery
- Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions
- Each Y family polymerase has a unique DNA-damage bypass and fidelity profile
- POLK is specialized for the extension step of lesion bypass.