Phospho-IKK E (Thr501)Rabbit anti-Human, Polyclonal, Rockland™
Manufacturer: Rockland Immunochemicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-1694-Each-of-1 | In Stock | ₹ 52,930.08 |
50-199-1694 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,930.08
GST (18%): ₹ 9,527.414
Total Price: ₹ 62,457.494
Antigen
Phospho-IKK E (Thr501)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IKBKE
Gene Alias
AW558201; I-kappa-B kinase epsilon; IKBKE; Ikke; IKK-E; IKKepsilon; IKK-epsilon; Ikki; IKK-i; IKK-related kinase epsilon; Inducible I kappa-B kinase; inducible IkappaB kinase; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon; inhibitor of kappaB kinase epsilon; Inhibitor of nuclear factor kappa-B kinase subunit epsilon; KIAA0151; RP11-534L20.1
Host Species
Rabbit
Regulatory Status
RUO
Gene ID (Entrez)
9641
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.1% sodium azide; pH 7.2
Gene Accession No.
Q14164
Gene Symbols
IKBKE
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
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Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This phospho specific polyclonal antibody is specific for phosphorylated pT501 human IKKe
- Reactivity with non-phosphorylated IKKe is minimal
- Cross reactivity with pT501 phosphorylated IKKe from mouse, rat or other species has not been determined
- Nuclear factor kappa B (NF-kappa-B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses
- NF-kappa-B mediates the expression of a great variety of genes in response to extracellular stimuli
- NF-kappa-B is associated with Ikappa-B proteins in the cell cytoplasm, which inhibit NF-kappa-B activity
- Ikappa-B is phosphorylated by Ikappa-B kinase (IKK) complex that contains IKK-a, IKK-b, and IKK-gamma
- A novel molecule in the IKK complex was recently identified and designated IKK-iota/IKK-i
- IKK epsilon is required for the activation of NF-kappa-B by PMA and T cell receptors but not by TNF-a and IL-1
- IKK-iota/IKK-i message is expressed in a variety of tissues and is inducible by TNF-a, IL-1, and LPS.