50-209-0120

SOX11 Monoclonal Antibody (SOX11-C1), eFluor™ 660, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each 50-209-0120-Each In Stock ₹ 38,861.85

50-209-0120 - Each

₹ 38,861.85

In Stock

Quantity

1

Base Price: ₹ 38,861.85

GST (18%): ₹ 6,995.133

Total Price: ₹ 45,856.983

Antigen

SOX11

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P35716

Gene Symbols

SOX11

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6664

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone

SOX11-C1

Conjugate

eFluor 660

Gene

SOX11

Gene Alias

1110038H03Rik; 6230403H02Rik; AI836553; end1; MRD27; Sox11; Sox-11; SRY; SRY (sex determining region Y)-box 11; SRY (sex-determining region Y)-box 11; SRY-box 11; SRY-box containing gene 11; SRY-box transcription factor 11; SRY-related HMG-box gene 11; transcription factor SOX-11

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The monoclonal antibody SOX11-C1 (C1) recognizes human Sox11
  • The transcription factor Sox11 is a member of the SOX (sex determining region Y-related HMG (High Mobility Group) Box) family of proteins
  • Under normal conditions Sox11 is expressed in the developing central nervous system during embryogenesis and has sequence homology to Sox4
  • Sox11 plays a role in neuronal maturation and epithelial-mesenchymal interactions and is required for the survival of neuronal and mesenchymal progenitor cells
  • Sox11 is expressed in mantle cell lymphoma (MCL) and in subsets of hairy cell leukemias, Burkitt lymphomas, and B cell lymphoblastic leukemias, but is not expressed in other B cell lymphomas or in normal B lymphocytes
  • Sox11 is also expressed in epithelial ovarian cancer and gliomas
  • Applications Reported: This SOX11-C1 antibody has been reported for use in immunohistochemical staining of formalin-fixed paraffin embedded tissue sections, immunocytochemistry and flow cytometric analysis
  • Applications Tested: This SOX11-C1 antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded human tissue using low or high pH antigen retrieval and can be used at less than or equal to 10 μg/mL
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interst
  • eFluor™ 660 is a replacement for Alexa Fluor™ 647
  • eFluor™ 660 emits at 659 nm and is excited with the red laser (633 nm)
  • This intronless gene encodes a member of the SOX family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate
  • The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins
  • The protein may function in the developing nervous system and play a role in tumorigenesis.