LIGHT Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-271-8524-Each-of-1 | In Stock | ₹ 1,75,552.50 |
50-271-8524 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,75,552.50
GST (18%): ₹ 31,599.45
Total Price: ₹ 2,07,151.95
Antigen
LIGHT
Classification
Polyclonal
Conjugate
Biotin
Gene
TNFSF14
Gene Alias
CD258; Herpes virus entry mediator ligand; herpesvirus entry mediator ligand; HVEML; HVEM-L; Light; LTg; Ly113; sCD258; sLIGHT; soluble CD258; soluble LIGHT; Tnfsf14; TR2; tumor necrosis factor (ligand) superfamily, member 14; tumor necrosis factor ligand 1D; tumor necrosis factor ligand superfamily member 14; Tumor necrosis factor ligand superfamily member 14, membrane form; Tumor necrosis factor ligand superfamily member 14, soluble form; tumor necrosis factor superfamily member 14; UNQ391/PRO726
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
50930
Content And Storage
-20°C
Isotype
IgG
Applications
Western Blot, ELISA
Concentration
0.1-1.0 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q9QYH9
Gene Symbols
TNFSF14
Immunogen
E.coli-derived Recombinant Murine LIGHT
Quantity
500μg
Primary or Secondary
Primary
Target Species
Mouse
Form
Lyophilized
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Description
- AA Sequence of recombinant protein: MRLHQRLGDI VAHLPDGGKG SWEKLIQDQR SHQANPAAHL TGANASLIGI GGPLLWETRL GLAFLRGLTY HDGALVTMEP GYYYVYSKVQ LSGVGCPQGL ANGLPITHGL YKRTSRYPKE LELLVSRRSP CGRANSSRVW WDSSFLGGVV HLEAGEEVVV RVPGNRLVRP RDGTRSYFGA FMV
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine LIGHT
- Anti-Murine LIGHT-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect Murine LIGHT by sandwich ELISA (using 100 μL/well) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine LIGHT (500-P308) as a capture antibody, allows the detection of at least 2000-4000 pg/mL of Recombinant Murine LIGHT
- Western Blot: To detect Murine LIGHT by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- When used in conjunction with compatible secondary reagents the detection limit for Recombinant Murine LIGHT is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P308BT-1MG will be provided as 2 x 500 μg Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms
- Apoptosis is induced by certain cytokines including TNF (tumor necrosis factor) and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 (tumor necrosis factor receptor 1) and Fas
- Cell death signals are transduced by death domain (DD)-containing adapter molecules and members of the ICE (interleukin-1-beta converting enzyme)/CED-3 (C
- elegans death receptor-3) protease family
- A novel DD-containing molecule was recently cloned from mouse, human and monkey and designated Daxx (death associated protein 6)
- Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway
- Daxx is widely expressed in fetal and adult human and mouse tissues indicating its important function in Fas signaling pathways.