CD26 Monoclonal Antibody (2A6), FITC, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-950-5-Each-of-1 | In Stock | ₹ 23,496.00 |
50-950-5 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,496.00
GST (18%): ₹ 4,229.28
Total Price: ₹ 27,725.28
Antigen
CD26
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P27487
Gene Symbols
DPP4
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1803
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
2A6
Conjugate
FITC
Gene
DPP4
Gene Alias
ACT3; Activation molecule 3; ADABP; ADCP2; ADCP-2; ADCP-I; adenosine deaminase complexing protein; Adenosine deaminase complexing protein 2; bile canaliculus domain-specific membrane glycoprotein; CD26; Dipeptidyl peptidase 4; Dipeptidyl peptidase 4 60 kDa soluble form; Dipeptidyl peptidase 4 membrane form; Dipeptidyl peptidase 4 soluble form; Dipeptidyl peptidase IV; Dipeptidyl peptidase IV 60 kDa soluble form; Dipeptidyl peptidase IV membrane form; Dipeptidyl peptidase IV soluble form; dipeptidylpeptidase 4; dipeptidyl-peptidase 4; dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2); dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); DPP IV; DPP4; Dpp-4; DPPIV; DPP-IV; GP110 glycoprotein; I79_016618; serine protease; T-cell activation antigen CD26; THAM; Thymocyte-activating molecule; TP103; WC10
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The 2A6 monoclonal antibody reacts with human CD26, a 110 kDa type II transmembrane dimer
- CD26 is an ectoenzyme with dipeptidyl peptidase IV activity expressed by T cells and is upregulated upon T cell stimulation
- It is thought that CD26 plays a role in interaction with the extracellular matrix molecules and in T cell activation
- Applications Reported: The 2A6 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 2A6 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
- This can be used at 5 μL (1 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser
- Filtration: 0.2 μm post-manufacturing filtered
- CD26 (dipeptidyl peptidase IV, DPP IV), adenosine deaminase (ADA) binding protein) is a homodimeric atypical serine protease belonging to the prolyl oligopeptidase family
- CD26 is expressed on lymphocyte cells and is upregulated during T-cell activation
- CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia
- CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection
- CD26 identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26
- Further, CD26 is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides
- Alterations in CD26 peptidase activity are characteristic of malignant transformation, and the enzymatic activity increases dramatically with tumor grade and severity
- CD26 is expressed in various blood cell types, but also in cells that are histogenetically related to activated fibroblasts
- Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.