CD200R3 Monoclonal Antibody (Ba13), Alexa Fluor™ 647, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 51-200-182-Each-of-1 | In Stock | ₹ 30,972.00 |
51-200-182 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,972.00
GST (18%): ₹ 5,574.96
Total Price: ₹ 36,546.96
Antigen
CD200R3
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q5UKY4
Gene Symbols
CD200R3
Immunogen
Mouse primary basophils
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
Ba13
Conjugate
Alexa Fluor 647
Gene
CD200R3
Gene Alias
4733401I18Rik; 4833409J19Rik; AI505817; BB106877; CD200 cell surface glycoprotein receptor 3; CD200 cell surface glycoprotein receptor-like 3; CD200 cell surface glycoprotein receptor-like b; CD200 receptor 3; CD200 receptor-like 3; Cd200r3; CD200RLb; cell surface glycoprotein CD200 receptor 3; Cell surface glycoprotein OX2 receptor 3; mCD200RLb
Host Species
Rat
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
74603
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
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Description
- Description: This Ba13 monoclonal antibody recognizes mouse CD200R3, a surface receptor expressed by basophils and mast cells
- Applications Reported: This Ba13 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This Ba13 antibody has been tested by flow cytometric analysis of MC/9 cell line
- This may be used at less than or equal to 0.25 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser
- CD200R3 is a dimeric cell surface receptor also known as CD200RLb
- CD200R3 contains two Ig-like extracellular domains and as such is a member of the immunoglobulin superfamily of receptors
- The intracellular region of CD200R3 associates with the adaptor molecule DAP12, and possibly also DAP10, CD3 zeta and FcR gamma-chain, indicating that it is capable of transducing stimulatory signals
- In this respect CD200R3 bears similarity to activatory receptors CD200R2 and CD200R4
- In contrast, an inhibitory receptor CD200R (also known as CD200R1) relies on other adaptors
- CD200R3 is primarily expressed by basophils and mast cells, cells known to be involved in anti-parasitic immune responses and frequently also allergic reactions
- The surface expression of CD200R3 decreases when basophils are activated by ligating their CD16 and CD32
- Remarkably, most of this downregulation is observed within the first 30 minutes after activation
- Unlike CD200R, CD200R3 does not bind CD200.