E4BP4 (NFIL3) Monoclonal Antibody (S2M-E19), Alexa Fluor™ 647, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 51-592-782-Each-of-1 | In Stock | ₹ 37,469.00 |
51-592-782 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,469.00
GST (18%): ₹ 6,744.42
Total Price: ₹ 44,213.42
Antigen
E4BP4 (NFIL3)
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.
O08750
Gene Symbols
NFIL3
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18030
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
S2M-E19
Conjugate
Alexa Fluor 647
Gene
NFIL3
Gene Alias
AV225605, E4 promoter binding-protein 4, E4 promoter-binding protein 4, E4BP4, Embryo implantation-related NFIL3/E4BP4-like transcription factor, IL3BP1, Interleukin-3 promoter transcriptional activator, interleukin-3-binding protein 1, NF IL3A, NFIL3, NFIL3A, NF-IL3A, nuclear factor interleukin 3 regulated protein, nuclear factor interleukin-3-regulated protein, nuclear factor, interleukin 3 regulated, nuclear factor, interleukin 3, regulated, OTTHUMP00000021633, transcriptional activator NF-IL3A
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
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Description
- Description: This S2M-E19 monoclonal antibody recognizes mouse E4BP4 (NFIL3), a basic leucine zipper transcription factor first identified for its binding to the promoters of the adenovirus E4 protein and human IL-3
- E4BP4 is involved in the transcriptional control of the mammalian circadian clock, motor neuron growth and survival, regulation of von Willbrand factor expression, and osteoblast function
- In addition, it is also required for the development of NK and NKT cells as well as CD8a+ dendritic cells
- Although relatively high levels of mRNA are reported in resting NK and NKT cells, studies at eBioscience have observed expression of E4BP4 protein in lymphocytes only after activation
- Applications Reported: This S2M-E19 antibody has been reported for use in intracellular staining followed by flow cytometric analysis
- Applications Tested: This S2M-E19 antibody has been tested by intracellular staining followed by flow cytometric analysis of stimulated mouse splenocytes using the Foxp3/Transcription Factor Staining Buffer Set (Product No
- 00-5523-00) and protocol
- Please refer to Staining Intracellular Antigens for Flow Cytometry, Protocol B: One step protocol for intracellular (nuclear) proteins located at www.thermofisher.com/flowprotocols
- This may be used at less than or equal to 0.5 μg per test
- Expression of interleukin-3 (IL3; MIM 147740) is restricted to activated T cells, natural killer (NK) cells, and mast cell lines
- Transcription initiation depends on the activating capacity of specific protein factors, such as NFIL3, that bind to regulatory regions of the gene, usually upstream of the transcription start site (Zhang et al., 1995 [PubMed 7565758]).