51-655-7100UL

MilliporeSigma™ anti-PGC-1, C-Terminal (777-797), Polyclonal

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 51-655-7100UL-Each-of-1 In Stock ₹ 56,084.24

51-655-7100UL - Each of 1

₹ 56,084.24

In Stock

Quantity

1

Base Price: ₹ 56,084.24

GST (18%): ₹ 10,095.163

Total Price: ₹ 66,179.403

Antigen

PGC-1, C-Terminal (777-797)

Classification

Polyclonal

Formulation

In PBS.

Immunogen

a synthetic peptide [(C)SKYDSLDFDSLLKEAQRSLRR] corresponding to amino acids 777-797 of the human PPARγ Coactivator 1 protein

Regulatory Status

RUO

Test Specificity

Recognize the ∽92 to 105kDa (apparent MW) PGC-1 protein.

Content And Storage

≤ -70°C

Isotype

IgG

Applications

ELISA, Immunoblot, Immunoblot, Immunohistochemistry

Conjugate

Unconjugated

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Purified

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Description

  • Specifically detects PGC-1, C-Terminal (777-797) Clone: in Human, Mouse samples, and it is validated for ELISA, Immunohistochemistry, Immuno Blotting PGC-1 (PPARγ-coactivator-1) is a coactivator that promotes transcription through the formation of a complex that includes steroid receptor coactivator-1 (SRC-1) and CREB binding protein (CBP)/p300
  • The binding of PGC-1 to the hinge domain of PPAR (peroxisome proliferator activated receptor) stimulates a conformational change in PGC-1 that permits binding of SRC-1 and CBP/p300, resulting in a large increase in transcriptional activity
  • Murine PGC-1 has been also reported to enhance the expression of uncoupling protein-1.