beta-3 Tubulin Monoclonal Antibody (2G10-TB3), Alexa Fluor™ 488, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 53-451-080-Each-of-1 | In Stock | ₹ 15,931.00 |
53-451-080 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 15,931.00
GST (18%): ₹ 2,867.58
Total Price: ₹ 18,798.58
Antigen
beta-3 Tubulin
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q13509, Q2T9S0, Q4QRB4, Q9ERD7
Gene Symbols
TUBB3
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10381, 22152, 246118, 768070
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone
2G10-TB3
Conjugate
Alexa Fluor 488
Gene
TUBB3
Gene Alias
3200002H15Rik; beta 3 tubulin; beta tubulin 3; beta-4; betaIII-tubulin; CDCBM; CDCBM1; CFEOM3; CFEOM3A; class III beta-tubulin; FEOM3; I79_000194; LOC100341581; M(beta)3; M(beta)6; mc1R; melanocortin receptor 1; Neuron specific beta III Tubulin; neuron-specific class III beta-tubulin; TUBB; Tubb3; TUBB4; tubulin beta; tubulin beta 3 class III; Tubulin beta-3; tubulin beta-3 chain; Tubulin beta-4; Tubulin beta-4 chain; tubulin beta-III; tubulin, beta 3 class III; tubulin, beta, 3; tubulin, beta, 4; Unknown (protein for MGC:134115)
Host Species
Mouse
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Bovine, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The 2G10 monoclonal antibody recognizes beta tubulin class III, a member of the large family of tubulins that are components of the microtubules of the cytoskeletal network
- Beta tubulin class III expression is exclusively found in neuronal cells of adult mammals
- Although expression has been mainly found in neuronal cells, during fetal development, transient expression has been documented in both glial and neuronal precursors localized to the subventricular zone
- Identification of beta tubulin class III expression is useful as a structural marker for developing and mature neural cells
- Given the high degree of conservation of this protein across species, the 2G10 clone is expected to recognize human, mouse, rat, and bovine beta tubulin class III
- Applications Reported: This 2G10-TB3 antibody has been reported for use in immunohistochemical staining of frozen tissue sections, immunohistochemical staining of formalin-fixed paraffin embedded tissue sections, microscopy, and immunocytochemistry
- Applications Tested: This 2G10-TB3 antibody has been tested by immunocytochemistry of formaldehyde-fixed and permeabilized cells and can be used at less than or equal to 10 μg/mL
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser
- Filtration: 0.2 μm post-manufacturing filtered
- The betaIII-tubulin isoform is present dominantly in cells of neuronal origin and it is one of the earliest markers of neuronal differentiation
- It is regarded as a specific probe for the cells of neuronal origin as well as for the tumours originating from these cells
- The betaIII-tubulin is most abundant in cells of neuronal origin, but was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues.