55-930-910T

MilliporeSigma™ anti-PhosphoDetect SAPK/JNK (pThr183, Tyr185), Polyclonal

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 55-930-910T-Each-of-1 In Stock ₹ 62,018.76

55-930-910T - Each of 1

₹ 62,018.76

In Stock

Quantity

1

Base Price: ₹ 62,018.76

GST (18%): ₹ 11,163.377

Total Price: ₹ 73,182.137

Antigen

PhosphoDetect™ SAPK/JNK (pThr183, Tyr185)

Classification

Polyclonal

Formulation

In Dulbecco's PBS (without Mg2+and Ca2+), 50% glycerol, 1mg/mL BSA, pH 7.3.

Immunogen

a synthetic phosphopeptide corresponding to amino acids surrounding the Thr183and Tyr185phosphorylation sites of human SAPK/JNK

Regulatory Status

RUO

Test Specificity

Recognizes the ∽49kDa SAPK1 protein and the ∽55kDa SAPK2 protein phosphorylated at Thr183and Tyr185. Antibody Target Gene Symbol: MAPK8, MAPK9 Target Synonym: AI849689, C-JUN N-TERMINAL KINASE1, JNK, JNK1, JNK1 PROTEIN KINASE, JNK1A2, JNK21B1/2, p46JNK1, p46JNK1 ALPHA, PRKM8, Sapk gamma, SAPK P46, SAPK1, SAPK1/JNK, STRESS-ACTIVATED PROTEIN KINASE-LIKE KINASE, AI851083, Jnk p54, Jnk p55, JNK-55, JNK2, JNK2A, Jnk2a2, JNK2ALPHA, JNK2B, JNK2BETA, JUNKINASE, p54a, p54aSAPK, PRKM9, SAPK, SAPK ALPHA, SAPK ALPHA 1 Entrez Gene Name: mitogen-activated protein kinase 8

Content And Storage

≤ -70°C

Isotype

IgG

Applications

Immunohistochemistry

Conjugate

Unconjugated

Host Species

Rabbit

Quantity

10 Tests

Primary or Secondary

Primary

Target Species

C. elegans, Chicken, Drosophila, Human, Mouse, Rat

Form

Purified

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Description

  • Specifically detects PhosphoDetect™ SAPK/JNK (pThr 183 , Tyr 185 ) Clone: in C
  • elegans, Chicken, Drosophila, Human, Mouse, Rat samples, and it is validated for Immunohistochemistry C-Jun-N-terminal kinase (JNK), also called stress-activated protein kinase (SAPK) is a member of the mitogen activated protein kinase (MAPK) family
  • JNK is activated in response to various extracellular stimuli, including pro-inflammatory cytokines
  • Phosphorylation of threonine and tyrosine in the Thr-Pro-Tyr domain is required for full activation
  • Mitogen activated protein kinase kinase (MKK4) preferentially phosphorylates tyrosine 185, and MKK7 causes preferential phosphorylation of threonine 183.