DNA Antibody (DSD/958), Novus Biologicals™

DNA

0.2mg/mL

Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry

Unconjugated

Mouse

Human

Double stranded deoxyribonucleic acid, Double stranded DNA, dsDNA

IgG3 κ

Protein A or G purified

This MAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This MAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells. Deoxyribonucleic acid (DNA) is a nucleic acid that stores long-term information regarding the development and function of all known living organisms. DNA consists of two long nucleotide polymers, which are composed of four bases, namely adenine, thymine, guanine and cytosine, all of which are flanked by a phosphate-deoxyribose backbone. Normally, DNA exists as a double-stranded (ds) molecule that forms in the shape of a double helix, allowing the bases and the backbone of the two strands to interact, thus forming a polynucleotide. When the double helix is unwound (either by enzymes or heat), DNA exists as a single-stranded (ss) molecule that is less stable than the double helix, but is necessary for protein access to

DSD/958

Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, Immunofluorescence 1 - 2 ug/ml, Immunocytochemistry 0.5 - 1.0 ug/ml

Monoclonal

Purified

RUO

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Nuclei of Burkitt's cells

Primary

Store at 4C.