Podocalyxin Like Antibody (2A4), Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Podocalyxin Like
Concentration
0.2mg/mL
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Conjugate
Unconjugated
Host Species
Mouse
Research Discipline
Cancer, Cell Biology, Cellular Markers, Embryonic Stem Cell Markers, Hematopoietic Stem Cell Markers, Stem Cell Markers
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias
Gp200MGC138240, PCLP1, PCLP-1, PCLPGCTM-2 antigen, PCpodocalyxin, podocalyxin-like, Podocalyxin-like protein 1
Gene Symbols
PODXL
Isotype
IgM
Purification Method
Protein A or G purified
Test Specificity
Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
Clone
2A4
Dilution
Flow Cytometry 5 - 10 ul/million cells in 0.1ml, Immunohistochemistry-Paraffin 1:50 - 1:100, Immunofluorescence 1:25 - 1:50
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Human, Rat, Rabbit
Gene Accession No.
O00592
Gene ID (Entrez)
5420
Immunogen
A recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain of human podocalyxin.
Primary or Secondary
Primary
Content And Storage
Store at 4C.
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Description
- Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence Podocalyxin Like Monoclonal specifically detects Podocalyxin Like in Human, Rat, Rabbit samples
- It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.