TfR (Transferrin R) Antibody (TFRC/1149), Novus Biologicals™

TfR (Transferrin R)

0.2 mg/mL

Western Blot, Flow Cytometry, Immunofluorescence

Unconjugated

Mouse

Cell Biology, Cellular Markers, Hematopoietic Stem Cell Markers, Immunology, Signal Transduction, Stem Cell Markers

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

7037

Recombinant human TFRC protein

Primary

Store at 4C.

TFRC/1149

Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 1 - 2 ug/ml

Monoclonal

Purified

RUO

Human

CD71 antigen, CD71TRFR, p90, T9, TfR, TFR1, TR, transferrin receptor (p90, CD71), transferrin receptor protein 1, Trfr

TFRC

IgG1 κ

Protein A or G purified

It recognizes a ∼90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.