CD24 Monoclonal Antibody (eBioSN3 (SN3 A5-2H10)), Super Bright™ 645, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 64-024-742-Each-of-1 | In Stock | ₹ 33,909.00 |
64-024-742 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,909.00
GST (18%): ₹ 6,103.62
Total Price: ₹ 40,012.62
Antigen
CD24
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P25063
Gene Symbols
Cd24
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100133941
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
eBioSN3 (SN3 A5-2H10)
Conjugate
Super Bright 645
Gene
Cd24
Gene Alias
CD24; CD24 antigen; CD24 antigen (small cell lung carcinoma cluster 4 antigen); CD24 molecule; CD24A; CD24a antigen; cluster of differentiation 24; FLJ22950; FLJ43543; heat stable antigen; heat-stable antigen; HSA; Ly-52; Lymphocyte antigen 52; M1/69-J11D heat stable antigen; MGC75043; Nectadrin; nectadrin heat stable antigen; R13-Ag; Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen; X62 heat stable antigen
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The PC61.5 antibody reacts with mouse CD25, the 55 kDa interleukin-2 receptor alpha chain (IL-2R alpha)
- CD25 is expressed by early progenitors of the T and B lineage as well as by activated mature T and B lymphocytes
- By itself, CD25 binds IL-2 only with low affinity
- However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor
- Binding of IL-2 to both the high and low affinity classes of IL-2 receptor is inhibited by the PC61.5 antibody
- CD25 plays a role in lymphocyte differentiation and activation/proliferation
- Applications Reported: This PC61.5 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This PC61.5 antibody has been tested by flow cytometric analysis of mouse splenocytes
- This may be used at less than or equal to 0.25 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Super Bright 645 is a tandem dye that can be excited with the violet laser line (405 nm) and emits at 645 nm
- We recommend using a 660/20 bandpass filter
- Please make sure that your instrument is capable of detecting this fluorochrome
- CD24 is a two-chain glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed at multiple stages of B-cell development, beginning with the bone marrow pro-B-cell compartment and continuing through mature, surface Ig positive B-cells
- Plasma cell expression is very low or negative
- CD24 is also expressed on the majority of B-lineage acute lymphoblastic leukemias, B-cell CCLs and B-cell non-Hodgkin's lymphomas
- CD24 may play a role in regulation of B-cell proliferation and maturation, and control of autoimmunity.