TrkC Recombinant Rabbit Monoclonal Antibody (7H3L20), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 70-198-5-Each-of-1 | In Stock | ₹ 56,826.50 |
70-198-5 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 56,826.50
GST (18%): ₹ 10,228.77
Total Price: ₹ 67,055.27
Antigen
TrkC
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q16288, Q6VNS1
Gene Symbols
Ntrk3
Immunogen
Protein corresponding to Human NTRK3 (aa 200-429)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Clone
7H3L20
Conjugate
Unconjugated
Gene
Ntrk3
Gene Alias
AW125844; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); GP145-TrkC; neural receptor protein-tyrosine kinase (trkC); neurotrophic receptor tyrosine kinase 3; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 3; neurotrophin-3; NT-3 growth factor receptor; NTRK3; Ntrk3_tv3; TrkC; trk-C; trkC tyrosine kinase; tyrosine kinase receptor; tyrosine kinase receptor C
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18213, 4916
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody is predicted to react with Monkey, Mouse and Rat
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system
- Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1
- The different isoforms do not have identical signaling properties
- The protein is widely expressed, mainly in the nervous tissue
- The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain
- TRKC is subject to ligand-mediated auto-phosphorylation
- The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.