70-327-5
PUM1 Recombinant Rabbit Monoclonal Antibody (8H60L23), Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 70-327-5-Each-of-1 | In Stock | ₹ 42,720.00 |
70-327-5 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,720.00
GST (18%): ₹ 7,689.60
Total Price: ₹ 50,409.60
Antigen
PUM1
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide, pH 7.4
Gene Accession No.
Q14671, Q80U78
Gene Symbols
PUM1
Immunogen
Protein corresponding to human PUM1 [aa229-aa370]
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
8H60L23
Conjugate
Unconjugated
Gene
PUM1
Gene Alias
AA517475, HsPUM, KIAA0099, mKIAA0099, PUM1, PUMH, PUMH1, pumilio 1, pumilio homolog 1, pumilio RNA binding family member 1, pumilio RNA-binding family member 1, pumilio-1, PUML1, Pumm
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
80912, 9698
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody is predicted to react with Rat, Bovine
- PUM1 (pumilio homolog 1) is a sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets
- It is a member of the PUF family comprised of evolutionarily conserved RNA-binding proteins
- PUM1 binds to an RNA consensus sequence, the Pumilio Response Element (PRE), and 5'-UGUANAUA-3' that is related to the Nanos Response Element (NRE)
- PUM1 mediates post-transcriptonal repression of transcripts via different mechanisms - acts via direct recruitment of the CCR4-POP2-NOT deadenylase leading to translational inhibition and mRNA degradation
- Mutations to the gene can result in spinocerebellar ataxia 47.