70-344-4
Caveolin 3 Recombinant Rabbit Monoclonal Antibody (14H4L21), Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 70-344-4-Each-of-1 | In Stock | ₹ 48,950.00 |
70-344-4 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,950.00
GST (18%): ₹ 8,811.00
Total Price: ₹ 57,761.00
Antigen
Caveolin 3
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide, pH 7.4
Gene Accession No.
P51637, P51638, P56539
Gene Symbols
Cav3
Immunogen
Peptides corresponding to human Caveolin 3 [1) 4 -18 2) aa24-aa38 3) aa30-aa44]
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
14H4L21
Conjugate
Unconjugated
Gene
Cav3
Gene Alias
AI385751, CAV, Cav3, Cav-3, caveolin 3, caveolin-3, LGMD1C, LQT9, M-cav, M-caveolin, MGC126100, MGC126101, MGC126129, structural protein, VIP21, VIP-21
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
12391, 29161, 859
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody is predicted to react with Monkey, Cat, Bovine
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Caveolin-3 (CAV3) acts as a scaffolding protein within the caveolar membrane
- It interacts directly with G-protein alpha subunits and can functionally regulate their activity
- Caveolin-3 may also regulate voltage-gated potassium channels
- It also plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress
- Caveolin-3 also mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae
- Mutations in the gene can result in HyperCKmia, rippling muscle disease 2, cardiomyopathy, long QT syndrome 9, sudden infant death syndrome, and myopathy.