70-336-0

H3.3 G34R oncohistone mutant Recombinant Rabbit Monoclonal Antibody (4H1L8), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 70-336-0-Each-of-1 In Stock ₹ 42,720.00

70-336-0 - Each of 1

₹ 42,720.00

In Stock

Quantity

1

Base Price: ₹ 42,720.00

GST (18%): ₹ 7,689.60

Total Price: ₹ 50,409.60

Antigen

H3.3 G34R oncohistone mutant

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

P84243

Gene Symbols

H3-3A, H3-3B

Immunogen

Peptides corresponding to human Histone H3.3 G34R/V [1)aa7-aa15 2)aa7-aa15]

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

4H1L8

Conjugate

Unconjugated

Gene

H3-3A

Gene Alias

H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3.3; H3.3 G34R; H3.3A; H3.3B; H3/g; H3-3A; H3-3B; H3B; H3F3; H3F3A; H3F3B; H3FT; H3t; Histone 3.3; Histone cluster 3; Histone H3; Histone H3.3; Histone H3.3 G34R; Histone H3.3G34R; PP781

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3020, 3021

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with Monkey, Frog
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes
  • Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4)
  • The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures
  • This gene is intronless and encodes a member of the histone H3 family
  • Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element
  • This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.