70-355-1

Histone H1.4 Recombinant Rabbit Monoclonal Antibody (22H1L5), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each 70-355-1-Each In Stock ₹ 36,369.85

70-355-1 - Each

₹ 36,369.85

In Stock

Quantity

1

Base Price: ₹ 36,369.85

GST (18%): ₹ 6,546.573

Total Price: ₹ 42,916.423

Antigen

Histone H1.4

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

P10412

Gene Symbols

H1-4, HIST1H1E

Immunogen

Peptides corresponding to human H1.4 [1) aa21-aa33 2) aa164-aa176]

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

ChIP Assay, Immunocytochemistry

Clone

22H1L5

Conjugate

Unconjugated

Gene

H1-4

Gene Alias

dJ221C16.5; H1 histone family, member 4; H1 VAR.2; H1.12 linker histone, cluster member; H1.4; H1-12; H14; H1-4; H1d; H1e; H1f4; H1s-4; H1var2; Hist1h1c; Hist1h1d; Hist1h1e; histone 1, H1e; Histone 1d; Histone cluster 1; histone cluster 1, H1d; histone cluster 1, H1e; histone H1.2; histone H1.4; Histone H1b; histone H1e; histone H1s-4; MGC116819

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3008

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with Monkey, Bovine, Pig
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes
  • Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes
  • The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures
  • This gene is intronless and encodes a member of the histone H1 family
  • Transcripts from this gene lack polyA tails but instead contain a palindromic termination element
  • This gene is found in the large histone gene cluster on chromosome 6.