JMJD2C Recombinant Rabbit Monoclonal Antibody (23H4L4), Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 70-338-0-Each-of-1 | In Stock | ₹ 42,720.00 |
70-338-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,720.00
GST (18%): ₹ 7,689.60
Total Price: ₹ 50,409.60
Antigen
JMJD2C
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide, pH 7.4
Gene Accession No.
Q9H3R0
Gene Symbols
KDM4C
Immunogen
Peptides corresponding to human KDM4C [1) aa1019-aa1038 2) aa494-aa513]
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
23H4L4
Conjugate
Unconjugated
Gene
KDM4C
Gene Alias
2410141F18Rik, AA517467, bA146B14.1, GASC1, GASC-1 protein, gene amplified in squamous cell carcinoma 1, gene amplified in squamous cell carcinoma 1 protein, JHDM3C, JmjC domain-containing histone demethylation protein 3C, JMJD2C, jumonji domain containing 2C, jumonji domain-containing protein 2C, Kdm4c, KIAA0780, lysine (K)-specific demethylase 4C, lysine demethylase 4C, lysine-specific demethylase 4C, RP11-169L18.1, TDRD14C, tudor domain containing 14C
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
23081
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- This antibody is predicted to react with Monkey, Pig, Cat, Sheep
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Jumonji domain-containing protein 2C (JMJD2C)/ Lysine-specific demethylase 4C (KDM4C) is a histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3; thereby, playing a central role in histone code
- KDM4C does not demethylate histone H3 'Lys-4', H3 'Lys-27', or H4 'Lys-20'
- It demethylates trimethylated H3 "eLys-9' and H3 "eLys-36' residues
- There is no activity on mono- or dimethylated residues
- Demethylation of Lys residues generates formaldehyde and succinate.