IGF2BP3 Recombinant Rabbit Monoclonal Antibody (6H33L68), Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 70-341-9-Each-of-1 | In Stock | ₹ 52,154.00 |
70-341-9 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,154.00
GST (18%): ₹ 9,387.72
Total Price: ₹ 61,541.72
Antigen
IGF2BP3
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.
O00425
Gene Symbols
IGF2BP3
Immunogen
Peptides corresponding to human IGF2BP3 [1) aa160-aa177 2) aa561-aa579]
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry
Clone
6H33L68
Conjugate
Unconjugated
Gene
IGF2BP3
Gene Alias
2610101N11Rik; AA522010; Ab2-255; AL022933; AU045931; cancer/testis antigen 98; CT98; hKOC; IGF2 mRNA-binding protein 3; IGF2BP3; IGF-II mRNA-binding protein 3; IMP3; IMP-3; insulin like growth factor 2 mRNA binding protein 3; insulin-l; insulin-like growth factor 2 mRNA binding protein 3; insulin-like growth factor 2 mRNA-binding protein 3; insulin-like growth factor 2, binding protein 3; KH domain containing protein overexpressed in cancer; KH domain-containing protein overexpressed in cancer; KOC; KOC1; Koc13; mimp3; mIMP-3; Neilsen; RGD1306512; VICKZ family member 3; Vickz3
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
10643
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody is predicted to react with Monkey, Cat, Dog
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family and is expressed during embryogenesis and in some malignancies
- IMP-3 is expressed in malignant melanoma but not in benign nevi, even when dysplastic features are present; IMP-3 is expressed in a significantly higher proportion of melanomas than Spitz nevi; and IMP-3 is expressed in metastatic melanomas significantly more than in thin melanomas
- IMP-3 appears to be involved in the progression of malignant melanoma and may play an important role in the regulation of the biologic behavior of this tumor.