70-355-4

TYRO3 Recombinant Rabbit Monoclonal Antibody (14H68L59), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 70-355-4-Each-of-1 In Stock ₹ 44,500.00

70-355-4 - Each of 1

₹ 44,500.00

In Stock

Quantity

1

Base Price: ₹ 44,500.00

GST (18%): ₹ 8,010.00

Total Price: ₹ 52,510.00

Antigen

TYRO3

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

P55144, P55146, Q06418

Gene Symbols

TYRO3

Immunogen

Protein corresponding to human TYRO3 [aa790-aa890]

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

14H68L59

Conjugate

Unconjugated

Gene

TYRO3

Gene Alias

AI323366; Brt; Bruton agammaglobulinemia tyrosine kinase; BYK; Dtk; Etk-2; etk2/tyro3; FLJ16467; Rek; Rse; Sky; soluble tyro 3; soluble tyro3; styro 3; styro3; TIF; TK19-2; tyro 3; TYRO3; TYRO3 protein tyrosine kinase; TYRO3 protein tyrosine kinase 3; tyrosine-protein kinase byk; Tyrosine-protein kinase DTK; tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase RSE; tyrosine-protein kinase SKY; Tyrosine-protein kinase TIF

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

22174, 25232, 7301

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with Monkey, Pig, Bovine, Cat
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6
  • It regulates many physiological processes including cell survival, migration, and differentiation
  • Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules
  • Following activation by a ligand, TYRO3 plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation, signal transduction, cell adhesion
  • and cytoskeleton reorganization.