70-378-4

alpha-II Spectrin Recombinant Rabbit Monoclonal Antibody (19H12L58), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each 70-378-4-Each In Stock ₹ 41,442.85

70-378-4 - Each

₹ 41,442.85

In Stock

Quantity

1

Base Price: ₹ 41,442.85

GST (18%): ₹ 7,459.713

Total Price: ₹ 48,902.563

Antigen

alpha-II Spectrin

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide, pH 7.4

Gene Accession No.

Q13813

Gene Symbols

SPTAN1

Immunogen

Protein corresponding to human SPTAN1 [aa2330-aa2472]

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

19H12L58

Conjugate

Unconjugated

Gene

SPTAN1

Gene Alias

(ALPHA)II-SPECTRIN, 2610027H02Rik, A2a, a--fodrin, alpha, alpha II spectrin, alpha-fodrin, alpha-II spectrin, alpha-spectrin, alpha-spectrin 2, alpha-spectrin 2, brain, brain, brain alpha-spectrin, EIEE5, FLJ44613, Fodrin alpha chain, inhibitory protein factor, IPF, NEAS, noerythroid alpha-spectrin 2, Non erythrocytic spectrin alpha, non-erythrocytic 1 (alpha-fodrin), non-erythroid alpha chain, nonerythroid alpha-spectrin, nonerythroid alpha-spectrin 2, putative alpha-spectrin, SPECA, Spectrin, Spectrin alpha, spectrin alpha chain, Spectrin alpha chain brain, spectrin alpha chain, brain, spectrin alpha chain, non-erythrocytic 1, spectrin alpha, non-erythrocytic 1, spectrin, alpha, non-erythrocytic 1, spectrin, alpha, non-erythrocytic 1 (alpha-fodrin), spectrin, non-erythroid alpha chain, spectrin, non-erythroid alpha subunit, Spna2, Spna-2, Spta2, Sptan1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

6709

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with Monkey, Bovine, Horse
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • SPTAN1 (spectrin alpha chain, non-erythrocytic 1) is a part of the spectrin family of filamentous cytoskeletal proteins
  • They function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles
  • Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement
  • SPTAN1 has been implicated in other cellular functions including DNA repair and cell cycle regulation
  • Mutations in this gene are the cause of early infantile epileptic encephalopathy-5
  • Alternate splicing results in multiple transcript variants.