70-392-8

GRPR Recombinant Rabbit Monoclonal Antibody (18H31L38), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 70-392-8-Each-of-1 In Stock ₹ 42,720.00

70-392-8 - Each of 1

₹ 42,720.00

In Stock

Quantity

1

Base Price: ₹ 42,720.00

GST (18%): ₹ 7,689.60

Total Price: ₹ 50,409.60

Antigen

GRPR

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

P30550

Gene Symbols

GRPR

Immunogen

Peptides corresponding to human GRPR [aa364-aa384, aa4-aa19]

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry

Clone

18H31L38

Conjugate

Unconjugated

Gene

GRPR

Gene Alias

BB2; BB2R; bombesin receptor 2; gastrin releasing peptide receptor; gastrin-releasing peptide receptor; GRP receptor; GRP-preferring bombesin receptor; GRPR; GRP-R

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

2925

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with Mouse, Rat, Bovine
  • Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues
  • The effects of GRP are mediated through the gastrin-releasing peptide receptor
  • This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway
  • The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate
  • An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.