71-162-7
GPR68 Recombinant Polyclonal Antibody (13HCLC), Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 71-162-7-Each-of-1 | In Stock | ₹ 38,270.00 |
71-162-7 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,270.00
GST (18%): ₹ 6,888.60
Total Price: ₹ 45,158.60
Antigen
GPR68
Classification
Recombinant Polyclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.
Q15743
Gene Symbols
GPR68
Immunogen
Peptide corresponding to human GPR68 [aa159-aa171]
Quantity
100μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry
Clone
13HCLC
Conjugate
Unconjugated
Gene
GPR68
Gene Alias
BB131428; Brgr1; Brgrb; G protein-coupled receptor 68; GPR12A; Gpr68; G-protein coupled receptor 68; Ogr1; OGR-1; ovarian cancer G protein-coupled receptor, 1; ovarian cancer G-protein coupled receptor 1; Sphingosylphosphorylcholine receptor
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
8111
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody is predicted to react with Monkey, Rat, Rabbit, Horse
- Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific
- They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody
- While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains
- The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production
- GPR68 (also known as OGR1 - ovarian cancer G-protein coupled receptor 1) is a proton-sensing receptor involved in pH homeostasis
- It represents an osteoblastic pH sensor regulating the cell-mediated response to acidosis in bone
- GPR68 mediates its action by association with G proteins that stimulate inositol phosphate (IP) production or CA2+ mobilization
- The receptor is almost silent at pH 7.8 but fully activated at pH 6.8
- Also found to serve as a tumor suppressor in prostate cancer
- Mutations to the gene result in amelogenesis imperfecta, hypomaturation type 2A6.