CD5 Monoclonal Antibody (YKIX322.3), PE, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
CD5
Concentration
5 μL/Test
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias
alanyl (membrane) aminopeptidase; alanyl aminopeptidase; alanyl aminopeptidase, membrane; aminopeptidase M; Aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD antigen CD5; CD13; CD28; CD28 antigen (Tp44); CD28 molecule; Cd5; CD5 antigen; CD5 antigen (p56 62); CD5 antigen (p56-62); CD5 antigen p56-62; CD5 molecule; CD5 protein; CD74 antigen, invariant polypeptide of major; cell surface protein; costimulatory molecule B7 receptor CD28; fCD5; GP150; hAPN; LAP1; LEU1; Ly-1; Ly12; Ly-12; LyA; Ly-A; Lymphocyte antigen 1; Lymphocyte antigen CD5; lymphocyte antigen T1/Leu-1; Lyt-1; membrane alanyl aminopeptidase; microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; P150; Pan T cell; PEPN; T1; T-cell costimulatory molecule CD28; T-cell surface glycoprotein CD5; T-cell-specific surface glycoprotein CD28; unnamed protein product
Gene Symbols
Cd5
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Gene
Cd5
Clone
YKIX322.3
Applications
Flow Cytometry
Conjugate
PE
Host Species
Rat
Target Species
Canine
Gene Accession No.
0
Gene ID (Entrez)
612338
Isotype
IgG2a κ
Purification Method
Affinity chromatography
Product Type
Antibody
Related Products
Description
- Description: This YKIX322.3 monoclonal antibody reacts with canine CD5, also known as Ly-1
- CD5 is a 67-kDa type I transmembrane glycoprotein expressed on thymocytes and mature T cells
- Studies have demonstrated that NK cells in dogs also express CD5, but at lower levels
- In dogs, CD5 is not detectable on B cells or B cell lines
- Applications Reported: This YKIX322.3 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This YKIX322.3 antibody has been pre-titrated and tested by flow cytometric analysis of normal canine peripheral blood cells
- This can be used at 5 μL (0.25 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
- Filtration: 0.2 μm post-manufacturing filtered
- CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein
- CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas
- CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation
- CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes
- In lymph nodes, the main reactivity is observed in T cell areas
- CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells
- Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.