CD69 Monoclonal Antibody (FN50), APC, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD69
Concentration
5 μL/Test
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias
5830438K24Rik; Activation inducer molecule; activation inducer molecule (AIM/CD69); AI452015; AIM; BL-AC/P26; CD69; CD69 antigen; CD69 antigen (p60, early T-cell activation antigen); CD69 molecule; CLEC2C; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; EA1; early activation antigen CD69; early lymphocyte activation antigen; early T-cell activation antigen p60; GP32/28; leukocyte surface antigen Leu-23; MLR-3; VEA; Very Early Activation Antigen
Gene Symbols
CD69
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Gene
CD69
Clone
FN50
Applications
Flow Cytometry
Conjugate
APC
Host Species
Mouse
Target Species
Human
Gene Accession No.
Q07108
Gene ID (Entrez)
969
Isotype
IgG1 κ
Purification Method
Affinity chromatography
Product Type
Antibody
Related Products
Description
- Description: The FN50 monoclonal antibody reacts with human CD69, also known as very early activation antigen (VEA)
- CD69 is approximately 30 kDa and is expressed on the cell-surface as a disulfide-linked dimer
- CD69 is rapidly upregulated upon activation and expressed on lymphocytes, monocytes and platelets
- Applications Reported: This FN50 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This FN50 antibody has been pre-titrated and tested by flow cytometric analysis of stimulated normal human peripheral blood cells
- This can be used at 5 μL (0.015 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser
- Filtration: 0.2 μm post-manufacturing filtered
- CD69 (AIM, Active Inducer Molecule) is a gp28/34 disulfide bonded homodimer with a molecular weight of 60 kDa under non-reducing conditions
- CD69 contains one or two N linked oligosacaride and the molecule is present on activated platelets
- In normal peripheral blood a variable percentage of cells express the CD69 antigen, and it is involved in lymphocyte signal transduction
- Expression CD69 is induced upon activation of T lymphocytes, and may play a role in proliferation
- Furthermore, the protein may act to transmit signals in natural killer cells and platelets
- Alternative splicing results in multiple transcript variants of CD69
- Diseases associated with CD69 dysfunction include coccidiodomycosis and asthma.